重组人TIGIT蛋白

人

人胚胎肾细胞（HEK293）

A DNA sequence encoding the Human TIGIT/VSIG9/VSTM3 Met22-Pro141 is expressed with a 6His tag at the C-terminus.

>95% as determined by SDS-PAGE.

VSIG9; VSTM3

T-cell immunoreceptor with Ig and ITIM domains(TIGIT)

TIGIT (also called T cell immunoreceptor with Ig and ITIM domains) is one newly discovered immune receptor on some percentage of T cells and Natural Killer Cells(NK). It is also identified as WUCAM and Vstm3. TIGIT could bind to CD155(PVR) on dendritic cells(DCs), macrophages, etc. with high affinity, and also to CD112(PVRL2) with lower affinity.

Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

<1.0 EU per μg protein as determined by the LAL method.

Lyophilized protein should be stored at <-20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days.