重组人VEGFA蛋白

人

杆状病毒 - 昆虫细胞

A DNA sequence encoding the human VEGF 183 isoform (P15692-3) (Met1-Arg209) was expressed.

> 95 % as determined by SDS-PAGE.

Measured in a cell proliferation assay using human umbilical vein endothelial cells
(HUVEC) (Conn, G. et al. 1990, Proc. Natl. Acad. Sci. USA 87:1323.). The ED₅₀ for this effect is typically 10-50 ng/ml.

The recombinant human VEGF 183 isoform consists of 183 amino acids and has a predicted molecular mass of 21 kDa.

MVCD1,VEGF,VEGF165,VPF

Vascular endothelial growth factor A

Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability, thus it was originally referred to as vascular permeability factor.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy

Lyophilized from sterile pH 7.92 100 mM glycine , 10 mM NaCl.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.

< 1.0 EU per μg protein as determined by the LAL method.

Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.