重组人VEGFA蛋白

产品详情

  • 产品名称
    重组人VEGFA蛋白
  • 蛋白种属
  • 表达宿主
    杆状病毒 - 昆虫细胞
  • Unitprot ID
  • 克隆构建
    A DNA sequence encoding the human VEGF 183 isoform (P15692-3) (Met1-Arg209) was expressed.
  • 蛋白纯度
    > 95 % as determined by SDS-PAGE.
  • 蛋白活性
    Measured in a cell proliferation assay using human umbilical vein endothelial cells
    (HUVEC) (Conn, G. et al. 1990, Proc. Natl. Acad. Sci. USA 87:1323.). The ED50 for this effect is typically 10-50 ng/ml.
  • 分子量
    The recombinant human VEGF 183 isoform consists of 183 amino acids and has a predicted molecular mass of 21 kDa.
  • 蛋白别名
    MVCD1,VEGF,VEGF165,VPF
  • 蛋白全名
    Vascular endothelial growth factor A
  • 蛋白描述
    Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability, thus it was originally referred to as vascular permeability factor.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
  • 发货形式
    Lyophilized from sterile pH 7.92 100 mM glycine , 10 mM NaCl.
    1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
    2. Please contact us for any concerns or special requirements.
  • 内毒素
    < 1.0 EU per μg protein as determined by the LAL method.
  • 保存条件
    Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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