Active against G+ bacteria S. aureus ATCC 6535, S. saprophyticus, B. subtilis CCT 2471 (MIC 10-15 ug/ml), and G- bacteria E. coli CCT 1371 (MIC 2.5 ug/ml), E. cloacae ACCT 23355, K. pneumoniae ACCT 13883, P. aeruginsa ACCT 27853 (MIC 10 ug/ml), and yeast C. albicans (MIC 2.5 ug/ml). Jelleines are produced constitutively by the workers and secreted into Royal Jelly. This peptide can show synergistic killing of Gram-positive bacteria with temporin A or B (Romanelli A et al 2011 Peptides Jan 19. doi: 10.1002/psc.1316). Updated Jan 2011; 7/2014. Jelleine-I has Antibacterial, Antifungal activity. The source of Jelleine-I is honeybees, Apis mellifera.
Fontana R, Mendes MA, De souza BM, et al. Jelleines: a family of antimicrobial peptides from the Royal Jelly of honeybees (Apis mellifera). Peptides. 2004;25(6):919-28.