重组人MND1蛋白

产品详情

  • 产品名称
    重组人MND1蛋白
  • 蛋白种属
  • 表达宿主
    大肠杆菌
  • Unitprot ID
  • 蛋白序列
    MSKKKGLSAEEKRTRMMEIFSETKDVFQLKDLEKIAPKEKGITAMSVKEVLQSLVDDGMVDCERIGTSNYYWAFPSKALHARKHKLEVLESQLSEGSQKHASLQKSIEKAKIGRCETEERTRLAKELSSLRDQREQLKAEVEKYKDCDPQVVEEIRQANKVAKEAANRWTDNIFAIKSWAKRKFGFEENKIDRTFGIPEDFDYIDLEHHHHHH
  • 克隆构建
    DNA encoding 2-205 aa (Q9BWT6) were fused with C-terminal 6His tag.
  • 蛋白纯度
    >85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
  • 蛋白活性
    Not tested.
  • 分子量
    Predictes a molecular mass of 24.80 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 29 kDa band.
  • 蛋白全名
    Meiotic nuclear division protein 1 homolog
  • 蛋白描述

    Recombinant Human Meiotic Nuclear Division Protein 1 Homolog (MND1) Fragment (aa 2-205) is a high-quality protein product designed for structural and biochemical studies. This stable and soluble fragment, derived from the MND1 gene, retains key functional regions essential for investigating homologous recombination and chromosome pairing mechanisms in meiosis.

    The full-length Meiotic Nuclear Division Protein 1 Homolog (MND1) is a nuclear protein crucial for proper homologous chromosome pairing and efficient crossover events during meiosis. It functions by stimulating both DMC1- and RAD51-mediated homologous strand assimilation, which is necessary for resolving meiotic double-strand breaks, thereby supporting accurate genetic recombination. This protein's role in promoting homologous recombination underscores its importance in maintaining genomic stability during gametogenesis.

  • 发货形式
    Lyophilized from sterile PBS, pH 7.4
  • 内毒素
    Please contact the lab for more information.
  • 保存条件
    Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
声明:本公司出售产品只能用于科研目的,不得用于诊断或者治疗!