Recombinant Human Prostate-associated microseminoprotein (PC3-secreted microprotein) Fragment (aa 36-139) is a high-purity, soluble protein designed for chemokine receptor research. This 104-amino acid fragment retains key functional regions, enabling studies on CCR2-mediated signaling, chemotaxis, and immune cell recruitment.

The full-length Prostate-associated microseminoprotein (MSMP) is a secreted human protein that functions as a ligand for the C-C chemokine receptor CCR2. Upon binding, it activates CCR2 to induce robust chemotactic responses and mobilize intracellular calcium ions. It demonstrates specific chemotactic activity for monocytes and lymphocytes but not neutrophils, highlighting its role in immune cell recruitment and inflammatory processes. As a secreted protein, it operates in extracellular environments, making it relevant for studying paracrine signaling in prostate biology and immune regulation.