重组人PDCD1LG2蛋白

产品详情

  • 产品名称
    重组人PDCD1LG2蛋白
  • 蛋白种属
    人
  • 表达宿主
    人胚胎肾细胞（HEK293）
  • Unitprot ID
    Q9BQ51
  • 蛋白序列
    Met 1 - Pro 219
  • 克隆构建
    A DNA sequence encoding the human PDCD1LG2 (NP_079515.2) (Met1-Pro219) was expressed with the Fc region of human IgG1 at the C-terminus.
  • 蛋白纯度
    > 95 % as determined by SDS-PAGE.
  • 蛋白活性
    1. Measured by its binding ability in a functional ELISA.
    2. Immobilized human PD1-His (Cat:503606) at 10 μg/mL (100 μL/well) can bind human PDCD1LG2-Fc. The EC50 of PDCD1LG2-Fc is 0.05-0.12 μg/mL.
  • 分子量
    The recombinant human PDCD1LG2 consists 438 amino acids and predicts a molecular mass of 49.3 kDa.
  • 蛋白别名
    BA574F11.2; BTDC; B7DC; B7-DC; MGC124039; PD-L2; PDCD1LG2; MGC124040; PDL2; MGC142240; CD273; PDCD1L2; F730015O22RIK; MGC142238
  • 蛋白全名
    Programmed cell death 1 ligand 2
  • 蛋白描述
    Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).
  • 发货形式
    Lyophilized from sterile PBS, pH 7.4.
    1. 5 % trehalose and mannitol are added as protectants before lyophilization.
    2. Please contact us for any concerns or special requirements.
  • 内毒素
    <1.0 EU per μg protein as determined by the LAL method.
  • 保存条件
    Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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