Recombinant Human Protein S100-A14 (S100 calcium-binding protein A14) fragment encompassing amino acids 1-104, designed to include the complete EF-hand domain. This high-purity protein is an essential tool for investigating the role of S100A14 in modulating P53/TP53 levels, regulating cell survival, apoptosis, and migration, making it ideal for functional assays and mechanistic studies.

Protein S100-A14, encoded by the S100A14 gene, is a multifunctional regulator that modulates P53/TP53 protein levels, influencing critical cellular processes such as cell survival, apoptosis, and proliferation. Depending on the context, it can promote either cell growth or programmed cell death. Additionally, it plays a role in cell migration by regulating the levels of MMP2, a matrix protease under P53/TP53 transcriptional control. Notably, this protein does not bind calcium and is primarily localized in the cytoplasm, as supported by experimental evidence. The provided recombinant fragment spans the full-length EF-h