H-RFCWKVCYKGICFKKCK-NH2 (C3-C16 and C7-C12 disulfide bonds)
三字母序列
H-Arg-Phe-Cys-Trp-Lys-Val-Cys-Tyr-Lys-Gly-Ile-Cys-Phe-Lys-Lys-Cys-Lys-Amidation (C3-C16 and C7-C12 disulfide bonds)
长度 (aa)
17
多肽纯度 (HPLC)
95.2
分子式
C99H155N27O18S4
分子量
2135.7
来源
固相合成
描述
Tachyplesin 1 (TP1; 1) is an antimicrobial peptide extracted from hemocytes of the Japanese horseshoe crab Tachypleus tridentatus.
Tachyplesin I displayed a potent activity against marine vibrios, with a MIC of 0.4-0.8 μg/ml against Vibrio P1.
It is highly hemolytic against mammalian erythrocytes, which precludes it from further development.