RMFPNAPYL is a linear peptidic epitope (epitope ID54882) studied as part of Wilms tumor protein from Homo sapiens (human). This epitope has been studied for immune reactivity, tested in T cell assays and MHC ligand assays WT-1 126-134 peptide RMFPNAPYL (HLA-A*02:01) for stimulation of T cells. Single peptide (RMFPNAPYL) for stimulation of human WT 1-specific CD8+ T cells.
Augsberger C, Hänel G, Xu W, Pulko V, Hanisch LJ, Augustin A, Challier J, Hunt K, Vick B, Rovatti PE, Krupka C, Rothe M, Schönle A, Sam J, Lezan E, Ducret A, Ortiz-Franyuti D, Walz AC, Benz J, Bujotzek A, Lichtenegger FS, Gassner C, Carpy A, Lyamichev V, Patel J, Konstandin N, Tunger A, Schmitz M, von Bergwelt-Baildon M, Spiekermann K, Vago L, Jeremias I, Marrer-Berger E, Umaña P, Klein C, Subklewe M. Targeting intracellular WT1 in AML with a novel RMF-peptide-MHC-specific T-cell bispecific antibody. Blood. 2021 Dec 23;138(25):2655-2669. doi: 10.1182/blood.2020010477. Erratum in: Blood. 2022 Mar 31;139(13):2086-2087. PMID: 34280257; PMCID: PMC9037755.