Recombinant Human ZBTB21 (1-119) fragment is a high-purity protein product encompassing the BTB domain of Zinc finger and BTB domain-containing protein 21. This fragment serves as an essential tool for investigating the domain-specific transcriptional repressor functions of ZBTB21 in cellular regulation.

Zinc finger and BTB domain-containing protein 21 (ZBTB21), encoded by the gene ZBTB21, functions as a transcription repressor, playing a key role in modulating gene expression. It is localized to the nucleus, where it colocalizes with ZBTB14 in HEK293 cells, indicating its involvement in nuclear regulatory complexes. The BTB domain, contained within this recombinant fragment (amino acids 30-96), is critical for protein-protein interactions and repression activity, making this product valuable for studying the mechanistic basis of ZBTB21-mediated transcriptional control.